| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene is a member of the DNA polymerase type-X familyand encodes a template-independent DNA polymerase that catalyzesthe addition of deoxynucleotides to the 3'-hydroxyl terminus ofoligonucleotide primers. In vivo, the encoded protein is expressedin a restricted population of normal and malignant pre-B and pre-Tlymphocytes during early differentiation, where it generatesantigen receptor diversity by synthesizing non-germ line elements(N-regions) at the junctions of rearranged Ig heavy chain and Tcell receptor gene segments. Alternatively spliced transcriptvariants encoding different isoforms of this gene have beendescribed. |
| Further Information: | This TDT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TDT. |
| Synonym: | DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase, DNTT, TDT |
| Ascension Number: | P04053 |
| NCBI EntrezGene: | 1791 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
