Applications: | IHC-P-Leica, WB |
Species Reactivity: | Human, Mouse, Rat |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | Capsaicin, the main pungent ingredient in hot chilipeppers, elicits a sensation of burning pain by selectivelyactivating sensory neurons that convey information about noxiousstimuli to the central nervous system. The protein encoded by thisgene is a receptor for capsaicin and is a non-selective cationchannel that is structurally related to members of the TRP familyof ion channels. This receptor is also activated by increases intemperature in the noxious range, suggesting that it functions as atransducer of painful thermal stimuli in vivo. Four transcriptvariants encoding the same protein, but with different 5' UTRsequence, have been described for this gene. |
Further Information: | This TRPV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-153 amino acids from the N-terminal region of human TRPV1. |
Synonym: | Transient receptor potential cation channel subfamily V member 1, TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, TRPV1, VR1 |
Ascension Number: | Q8NER1 |
NCBI EntrezGene: | 7442 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |