| Applications: | FC, IHC-P, WB |
| Species Reactivity: | Human, Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene encodes a bifunctional enzyme containingphosphoribosylaminoimidazole carboxylase activity in its N-terminalregion and phosphoribosylaminoimidazole succinocarboxamidesynthetase in its C-terminal region. It catalyzes steps 6 and 7 ofpurine biosynthesis. The gene is closely linked and divergentlytranscribed with a locus that encodes an enzyme in the samepathway, and transcription of the two genes is coordinatelyregulated. The human genome contains several pseudogenes of thisgene. Multiple transcript variants encoding different isoforms havebeen found for this gene. |
| Further Information: | This PAICS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the N-terminal region of human PAICS. |
| Synonym: | Multifunctional protein ADE2, Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase, Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC, PAICS, ADE2, AIRC, PAIS |
| Ascension Number: | P22234 |
| NCBI EntrezGene: | 10606 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
