Applications: | IHC-P, WB, FC |
Species Reactivity: | Human |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | The protein encoded by this gene acts as a guaninenucleotide exchange factor for the RHO family of small GTP-bindingproteins (RACs). It has been shown to bind to and activate RAC1 byexchanging bound GDP for free GTP. The encoded protein, which isfound mainly in the cytoplasm, is activated byphosphatidylinositol-3,4,5-trisphosphate and the beta-gammasubunits of heterotrimeric G proteins. |
Further Information: | This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1163 amino acids from the C-terminal region of human PREX1. |
Synonym: | Phosphatidylinositol 3,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,5)-dependent Rac exchanger 1, PREX1, KIAA1415 |
Ascension Number: | Q8TCU6 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |