Applications: | WB, IHC-P, IF |
Species Reactivity: | Human |
Isotype: | Rabbit IgG |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | Prostaglandin-endoperoxide synthase (PTGS), also known ascyclooxygenase, is the key enzyme in prostaglandin biosynthesis,and acts both as a dioxygenase and as a peroxidase. There are twoisozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2,which differ in their regulation of expression and tissuedistribution. This gene encodes the inducible isozyme. It isregulated by specific stimulatory events, suggesting that it isresponsible for the prostanoid biosynthesis involved ininflammation and mitogenesis. |
Further Information: | This PTGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-391 amino acids from the Central region of human PTGS2. |
Synonym: | Prostaglandin G/H synthase 2, Cyclooxygenase-2, COX-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, PTGS2, COX2 |
Ascension Number: | P35354 |
NCBI EntrezGene: | 5743 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |