| Applications: | FC, WB |
| Species Reactivity: | Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Purified Rabbit Polyclonal Antibody |
| Description: | The protein encoded by this gene belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases. Different cyclinsexhibit distinct expression and degradation patterns whichcontribute to the temporal coordination of each mitotic event. Thiscyclin forms a complex with CDK7 kinase and ring finger proteinMAT1. The kinase complex is able to phosphorylate CDK2 and CDC2kinases, thus functions as a CDK-activating kinase (CAK). Thiscyclin and its kinase partner are components of TFIIH, as well asRNA polymerase II protein complexes. They participate in twodifferent transcriptional regulation processes, suggesting animportant link between basal transcription control and the cellcycle machinery. A pseudogene of this gene is found on chromosome4. Alternate splicing results in multiple transcript variants. |
| Further Information: | This CCNH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human CCNH. |
| Synonym: | Cyclin-H, MO15-associated protein, p34, p37, CCNH |
| Ascension Number: | P51946 |
| NCBI EntrezGene: | 902 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
