| Applications: | WB, IF |
| Species Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene encodes a transcriptional regulator that formsnuclear bodies and interacts with the transcriptional coactivatorCBP. At least three splice variant mRNAs products have beendescribed including one which results in a premature stop codon anda transcript predicted to be a candidate for nuclear-mediated decay(NMD). Defects in this gene cause the rare autosomal-recessivesystemic autoimmune disease termed autoimmunepolyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). |
| Further Information: | This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE. |
| Synonym: | Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED |
| Ascension Number: | O43918 |
| NCBI EntrezGene: | 326 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
