| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene is directly involved, with Myc and IgH, in athree-way gene translocation in a Burkitt lymphoma cell line. As aresult of the gene translocation, the N-terminal region of the geneproduct is disrupted, which is thought to be related to thepathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma.The N-terminal segment involved in the translocation includes theregion that shares a strong sequence similarity with those of BCL7Band BCL7C. Two transcript variants encoding different isoforms havebeen found for this gene. |
| Further Information: | This BCL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A. |
| Synonym: | B-cell CLL/lymphoma 7 protein family member A, BCL7A |
| Ascension Number: | Q4VC05 |
| NCBI EntrezGene: | 605 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
