| Applications: | IHC-P, WB |
| Species Reactivity: | Human, Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | COL18A1 is the alpha chain of type XVIII collagen.This collagen is one of the multiplexins, extracellular matrixproteins that contain multiple triple-helix domains (collagenousdomains) interrupted by non-collagenous domains. Theproteolytically produced C-terminal fragment of type XVIII collagenis endostatin, a potent antiangiogenic protein. Mutations in thisgene are associated with Knobloch syndrome. The main features ofthis syndrome involve retinal abnormalities, so type XVIII collagenmay play an important role in retinal structure and in neural tubeclosure. |
| Further Information: | This COL18A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1311-1339 amino acids from the Central region of human COL18A1. |
| Synonym: | Collagen alpha-1(XVIII) chain, Endostatin, COL18A1 |
| Ascension Number: | P39060 |
| NCBI EntrezGene: | 80781 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
