| Applications: | FC, IHC-P, WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | Mammalian apolipoprotein B mRNA undergoes site-specific Cto U deamination, which is mediated by a multi-component enzymecomplex containing a minimal core composed of APOBEC-1 and acomplementation factor encoded by this gene. The gene product hasthree non-identical RNA recognition motifs and belongs to the hnRNPR family of RNA-binding proteins. It has been proposed that thiscomplementation factor functions as an RNA-binding subunit anddocks APOBEC-1 to deaminate the upstream cytidine. Studies suggestthat the protein may also be involved in other RNA editing or RNAprocessing events. |
| Further Information: | This ACF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human ACF. |
| Synonym: | APOBEC1 complementation factor, APOBEC1-stimulating protein, A1CF, ACF, ASP {ECO:0000312|EMBL:CAB947541} |
| Ascension Number: | Q9NQ94 |
| NCBI EntrezGene: | 29974 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
