Ordering Details
Cat Number:	AP10669c-ev
Size:	80uL
Price:	£117.00
Quantity:
Shipping:	£12.00

Document Links

Data Sheet

MSDS

CCNT1 [Centre] [RB19562], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:	WB, FC
Species Reactivity:	Human, Mouse
Isotype:	Rabbit Ig
Purification:	Affinity Purified Rabbit Polyclonal Antibody
Description:	CCNT1 belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases. Different cyclinsexhibit distinct expression and degradation patterns whichcontribute to the temporal coordination of each mitotic event. Thiscyclin tightly associates with CDK9 kinase, and was found to be amajor subunit of the transcription elongation factor p-TEFb. Thekinase complex containing this cyclin and the elongation factor caninteract with, and act as a cofactor of human immunodeficiencyvirus type 1 (HIV-1) Tat protein, and was shown to be bothnecessary and sufficient for full activation of viraltranscription. This cyclin and its kinase partner were also foundto be involved in the phosphorylation and regulation of thecarboxy-terminal domain (CTD) of the largest RNA polymerase IIsubunit.
Further Information:	This CCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids from the Central region of human CCNT1.
Synonym:	Cyclin-T1, CycT1, Cyclin-T, CCNT1
Ascension Number:	O60563
NCBI EntrezGene:	904
Shipping Conditions:	Ship on cold packs
Storage:	Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:	Research use only

Insight Biotechnology Ltd reserves the right to change pricing without notice

All lanes : Anti-CCNT1 Antibody (Center) at 1:1000 dilutionLane 1: Hela whole cell lysateLane 2: MCF-7 whole cell lysateLane 3: HL-60 whole cell lysateLane 4: Jurkat whole cell lysateLane 5: K562 whole cell lysateLane 6: SH-SY5Y whole cell lysateLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 81 kDaBlocking/Dilution buffer: 5% NFDM/TBST.