Applications: | FC, WB |
Species Reactivity: | Human, Mouse |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity). |
Further Information: | This BHLHA15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-189 amino acids from the C-terminal region of human BHLHA15. |
Synonym: | Class A basic helix-loop-helix protein 15, bHLHa15, Class B basic helix-loop-helix protein 8, bHLHb8, Muscle, intestine and stomach expression 1, MIST-1, BHLHA15, BHLHB8, MIST1 |
Ascension Number: | Q7RTS1 |
NCBI EntrezGene: | 168620 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |