| Applications: | FC, IHC-P, WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | ABCD1 is a member of thesuperfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- andintra-cellular membranes. ABC genes are divided into seven distinctsubfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Thisprotein is a member of the ALD subfamily, which is involved inperoxisomal import of fatty acids and/or fatty acyl-CoAs in theorganelle. All known peroxisomal ABC transporters are halftransporters which require a partner half transporter molecule toform a functional homodimeric or heterodimeric transporter. Thisperoxisomal membrane protein is likely involved in the peroxisomaltransport or catabolism of very long chain fatty acids. Defects inthis gene have been identified as the underlying cause ofadrenoleukodystrophy, an X-chromosome recessively inheriteddemyelinating disorder of the nervous system. |
| Further Information: | This ABCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human ABCD1. |
| Synonym: | ATP-binding cassette sub-family D member 1, Adrenoleukodystrophy protein, ALDP, ABCD1, ALD |
| Ascension Number: | P33897 |
| NCBI EntrezGene: | 215 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
