Applications: | IHC-P, WB |
Species Reactivity: | Human, Mouse |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | The multi-pass membrane protein encoded by this genebelongs to the G-protein coupled receptor 3 family and GABA-Breceptor subfamily. The GABA-B receptors inhibit neuronal activitythrough G protein-coupled second-messenger systems, which regulatethe release of neurotransmitters, and the activity of ion channelsand adenylyl cyclase. This receptor subunit forms an activeheterodimeric complex with GABA-B receptor subunit 1, neither ofwhich is effective on its own. Allelic variants of this gene havebeen associated with nicotine dependence. |
Further Information: | This GABBR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-890 amino acids from the C-terminal region of human GABBR2. |
Synonym: | Gamma-aminobutyric acid type B receptor subunit 2, GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51, HG20, GABBR2, GPR51, GPRC3B |
Ascension Number: | O75899 |
NCBI EntrezGene: | 9568 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |