| Applications: | FC, IHC-P, WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene encodes a member of the claudin family. Claudinsare integral membrane proteins and components of tight junctionstrands. Tight junction strands serve as a physical barrier toprevent solutes and water from passing freely through theparacellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity andsignal transductions. Differential expression of this gene has beenobserved in different types of malignancies, including breastcancer, ovarian cancer, hepatocellular carcinomas, urinary tumors,prostate cancer, lung cancer, head and neck cancers, thyroidcarcinomas, etc.. Alternatively spliced transcript variantsencoding different isoforms have been found. |
| Further Information: | This CLDN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the C-terminal region of human CLDN7. |
| Synonym: | Claudin-7, CLDN-7, CLDN7, CEPTRL2, CPETRL2 |
| Ascension Number: | O95471 |
| NCBI EntrezGene: | 1366 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
