| Applications: | WB |
| Species Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG1,? |
| Purification: | Purified Mouse Monoclonal Antibody |
| Description: | Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). |
| Further Information: | This CALR antibody is generated from a mouse immunized with a recombinant protein from human CALR. |
| Synonym: | Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, grp60, CALR (<a href=http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=1455 target=_blank>HGNC:1455</a>), CRTC |
| Ascension Number: | P27797 |
| NCBI EntrezGene: | 811 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
