| Applications: | FC, WB |
| Species Reactivity: | Human |
| Isotype: | IgG2b,? |
| Purification: | Purified Mouse Monoclonal Antibody |
| Description: | Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF. |
| Further Information: | This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-232 amino acids from human. |
| Synonym: | HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, Ii, p33, CD74, CD74, DHLAG |
| Ascension Number: | P04233 |
| NCBI EntrezGene: | 972 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
