| Applications: | WB |
| Species Reactivity: | Mouse |
| Isotype: | IgG2a |
| Purification: | Mouse Monoclonal Antibody |
| Description: | This gene encodes an enzyme involved in catalyzing theconversion of angiotensin I into a physiologically active peptideangiotensin II. Angiotensin II is a potent vasopressor andaldosterone-stimulating peptide that controls blood pressure andfluid-electrolyte balance. This enzyme plays a key role in therenin-angiotensin system. Many studies have associated the presenceor absence of a 287 bp Alu repeat element in this gene with thelevels of circulating enzyme or cardiovascular pathophysiologies.Multiple alternatively spliced transcript variants encodingdifferent isoforms have been identified, and two most abundantspliced variants encode the somatic form and the testicular form,respectively, that are equally active. |
| Further Information: | This ACE antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1274-1306 amino acids from human ACE. |
| Synonym: | Angiotensin-converting enzyme, ACE, 321-, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1 |
| Ascension Number: | P12821 |
| NCBI EntrezGene: | 1636 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
