Applications: | WB |
Species Reactivity: | Human |
Isotype: | IgG1 |
Purification: | Mouse Monoclonal Antibody |
Description: | This gene encodes the integrin alpha X chain protein.Integrins are heterodimeric integral membrane proteins composed ofan alpha chain and a beta chain. This protein combines with thebeta 2 chain (ITGB2) to form a leukocyte-specific integrin referredto as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2complex seems to overlap the properties of the alpha M beta 2integrin in the adherence of neutrophils and monocytes tostimulated endothelium cells, and in the phagocytosis of complementcoated particles. |
Further Information: | This ITGAX/CD11c antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human ITGAX/CD11c. |
Synonym: | Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C |
Ascension Number: | P20702 |
NCBI EntrezGene: | 3687 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |