| Applications: | ELISA, WB, IHC, ICC/IF |
| Species Reactivity: | Human |
| Isotype: | Mouse IgG1 kappa |
| Immunogen: | Recombinant human Hsp70 (1-641aa) purified from E. coli |
| Purification: | By protein-G affinity chromatography |
| Conjugation: | Unconjugated |
| Description: | Hsp70 is a human heat shock protein. Hsp70 is an important part of the cell's machinery for protein folding, and help to protect cells from stress. In most species, there are many proteins that belong to the hsp70 family. Some of these are only expressed under stress conditions, while some are present in cells under normal growth conditions and are not heat-inducible. Hsp70 can be found in different cellular compartments (nuclear, cytosolic, mitochondrial, endoplasmic reticulum, etc... ), and the chaperone function of hsp70 is required for protection against stress-induced apoptosis. |
| Further Information: | The antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500 ~ 1:2,000 and immunohistochemistry analysis is 1:100~200. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:100. |
| Synonym: | Heat shock 70 kDa protein 1, HSPA1A, HSPA1, HSPA1B, HSP70, HSP70.1, HSP70-1/HSP70-2, Heat shock 70 kDa protein 1, Heat shock 70 kDa protein 1, heat shock 70kDa protein 1A, |
| Ascension Number: | P0DMV8 |
| NCBI EntrezGene: | NP_005336 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
