| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 21.9 kDa (191 aa), confirmed by MALDI-TOF |
| Purity: | > 95% by SDS - PAGE |
| Description: | AGR2 (Anterior gradient 2 homolog) is the human orthologue of the secreted Xenopus laevis Anterior Gradient protein (XAG-2). This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Recombinant human AGR2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSRDTT VKPGAKKDTK DSRPKLPQTL SRGWGDQLIW TQTYEEALYK SKTSNKPLMI IHHLDECPHS QALKKVFAEN KEIQKLAEQF VLLNLVYETT DKHLSPDGQY VPRIMFVDPS LTVRADITGR YSNRLYAYEP ADTALLLDNM KKALKLLKTE L |
| Synonym: | Anterior gradient 2 homolog, AG2, GOB-4, HAG-2, XAG-2, Anterior gradient 2 homolog, AGR 2, Anterior gradient 2 homolog, AGR2, anterior gradient homolog 2 (Xenopus laevis), PDIA17, protein disulfide isomerase family A member 17, Anterior Gradient Protein 2 Homolog |
| Ascension Number: | O95994 |
| NCBI EntrezGene: | NP_006399 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
