| Applications: | ELISA, WB, ICC/IF, FACS |
| Species Reactivity: | Human |
| Isotype: | Mouse IgG1 kappa |
| Immunogen: | Recombinant human Cofilin 1 (1-166aa) purified from E. coli |
| Purification: | By protein-G affinity chromatography |
| Conjugation: | Unconjugated |
| Description: | Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
| Further Information: | The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000. |
| Synonym: | CFL1 CFL 18 kDa phosphoprotein(p18), CFL1, CFL, Cofilin 1, CFL1, CFL, 18 kDa phosphoprotein(p18) 18 kDa phosphoprotein, CFL 1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, P18. |
| Ascension Number: | P23528 |
| NCBI EntrezGene: | NP_005498 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
