XRCC5 Polyclonal Antibody
Partner: Epigentek Group Inc
| Applications: | WB, IHC, IF, IP, IHC |
| Description: | The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| Synonym: | XRCC5; KARP-1; KARP1; KU80; KUB2; Ku86; NFIV; X-ray repair cross complementing 5 |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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