ASCC1 Polyclonal Antibody
Partner: Epigentek Group Inc
| Applications: | WB, IF |
| Description: | This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. |
| Synonym: | ASCC1; ASC1p50; CGI-18; SMABF2; p50; activating signal cointegrator 1 complex subunit 1 |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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