| Applications: | IHC, WB |
| Species Reactivity: | Human |
| Isotype: | Sheep IgG |
| Immunogen: | This whole sheep serum was prepared by repeated immunizations with recombinant human Thymidylate Synthase (36 kDa) produced in E.coli. |
| Purification: | This antiserum is directed against human Thymidylate Synthase and is useful in determining its presence in various assays. Because inhibition of Thymidylate Synthase prevents DNA synthesis and cell proliferation, the enzyme is an important target for cancer chemotherapeutic drugs, specifically the fluoropyrimidine group of antineoplastic drugs used to treat solid tumors. In general, this antibody can detect antigen in a variety of human cells and tissues, as well as bacteria, African green monkey, rat and mouse. Somewhat lower dilutions may be required in some non-human cell lines.� Anti-Thymidylate Synthase can detect Thymidylate Synthase by immunochemistry in proliferating cell cultures and tissues but does not stain nonproliferating cells. Normal colon mucosa shows weak staining; however, some colorectal cancer specimens show very strong staining. |
| MW: | 35716 MW |
| Description: | Boster Bio Anti-Thymidylate Synthase TYMS Antibody (Catalog # A04320). Tested in IHC, WB applications. This antibody reacts with Human. |
| Synonym: | sheep anti-Thymidylate Synthase, HsT422, MGC88736, TMS, TS, TSase, TYMS, TYMS protein |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Store vial at 4 C prior to restoration. For extended storage aliquot contents and freeze at -20 C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 C as an undiluted liquid. Dilute only prior to immediate use.�Expiration date is one (1) year from date of opening. |
| Usage: | Research use only |
