| Applications: | Dot Blot, ELISA, IHC, WB |
| Species Reactivity: | Human, Mouse |
| Immunogen: | This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 1 located near the N-terminal sequence of the cleaved N intracellular domain (NICD). |
| Purification: | This antiserum is directed against human NOTCH 1. Based on the immunogen sequence, we expect this antibody to react as well with mouse and rat NOTCH 1 (100% sequence homology). This antibody reacts with mouse Notch constructs present in lysates of HEK 293 cells. Only the cleaved intracellular (activated) form (NICD) is detected. No reactivity is detected against mouse N2, N3 or N4. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form. |
| MW: | 272505 MW |
| Description: | Boster Bio Anti-NOTCH 1 Antibody (Catalog # A00033). Tested in Dot Blot, ELISA, IHC, WB applications. This antibody reacts with Human, Mouse. |
| Synonym: | notch1, Neurogenic locus Notch homolog protein 1, hN1, Translocation-associated Notch protein TAN-1 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Store vial at -20 C prior to opening. Aliquot contents and freeze at -20 C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening. |
| Usage: | Research use only |
