| Applications: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Reactivity (Predicted): | The antibody has not been showed to cross-react with LYVE-1 from mouse or other species. |
| Dilutions: | IHC: 1:100, WB: 1:200 |
| Isotype: | Rabbit IgG |
| Conjugation: | Unconjugated |
| Description: | LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. LYVE-1 is the first lymph-specific HA receptor to be characterized. Later, LYVE-1 was reported to express in liver sinusoid blood vessels. However, in most tissues, LVYE-1 is a specific marker for lymph vessels. |
| Further Information: | The antibody will detect human LYVE-1 on the surface of lymphatic endothelial cells by immunohistochemistry. The antibody detects a 70 KD LYVE-1 band in Western blotting. |
| Shipping Conditions: | Ship on cold packs |
| Storage: | The antibody should be stored at �20�C. |
| Usage: | Research use only |
