| Applications: | IF, IHC(f), IHC(p), WB |
| Species Reactivity: | Human |
| Reactivity (Predicted): | The antibody cross-reacts with rabbit VEGF. Other species not tested. |
| Dilutions: | WB: 1-2ug/ml, IHC: 1:50 (For paraffin embedded sections, boil tissue sections in 1mM EDTA buffer, pH 8.0 for 10-20 min followed by cooling at RT for 20 min to retrieve antigens.) |
| Isotype: | Mouse IgG1 |
| Purification: | Purified |
| Conjugation: | Unconjugated |
| Description: | VEGF (Vascular Endothelial Growth Factor) or VPF is the most important angiogenesis stimulator. It is a homodimeric, disulfide-linked glycoprotein which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium. Of the four isoforms of VEGF, the smaller two, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two (VEGF189 and VEGF206) remain cell associated. |
| Further Information: | The monoclonal antibody is raised against human VEGF121 and recognizes all forms of VEGF. It is suitable for neutralizing the bioactivity of human VEGF (please order antibody without sodium azide). The antibody also works in immunostaining or immunohistochemistry and Western blotting. |
| Shipping Conditions: | Ship on cold packs |
| Storage: | The antibody is stable at 4�C for 20 months. |
| Usage: | Research use only |
