Motesanib [CAS 453562-69-1] (10mM in DMSO)
Partner: MedChemexpress LLC
| CAS No: | 453562-69-1 |
| Applications: | Cancer-Kinase/protease |
| MW: | 373.45 |
| Formula: | C22H23N5O |
| SMILES: | O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC(NCC4(C)C)=C4C=C3 |
| Purity: | 99.96 |
| Description: | Motesanib (AMG 706) is a potent ATP-competitive inhibitor of�VEGFR1/2/3�with�IC50s�of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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