Description: | DS-01-0489 is an <i>E. coli</i>-derived recombinant protein corresponding to mature full-length human Platelet-Derived Growth Factor BB homodimer (PDGF-BB), a potent mitogen for cells of mesenchymal origin. PDGF is composed of a dimer of two chains, known as the A chain and B chain. The dimer may present as either AA or BB homodimer, or as an AB heterodimer.<br><br>DS-01-0489 has an ED<sub>50</sub> of 1.0-3.0 ng/ml as determined by stimulation of the proliferation of Balb/c 3T3 cells. |