Description: | Endo-?-N-acetylglucosaminidase D (Endo D), isolated from Streptococcus pneumoniae. Endo-?-N-acetylglucosaminidase D hydrolyzes Fc N-glycan of intact IgG antibodies after sequential removal of the sialic acid, galactose, and internal GlcNAc residues in the N-glycan. Endo-?-N-acetylglucosaminidase D possesses transglycosylation activity with sugar oxazoline as the donor substrate[1]. |