Dicer, Monoclonal Antibody
Partner: Aviva Systems Biology
| Applications: | WB, ICC, IF |
| Species Reactivity: | Human, Mouse, Rat |
| Dilutions: | WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user. |
| Immunogen: | Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer |
| Purification: | Protein G Purified |
| Conjugation: | Unconjugated |
| Description: | Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3) |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
Insight Biotechnology Ltd reserves the right to change pricing without notice
