| MW: | 15-19 kDa |
| Purity: | >98 % as determined by SDS-PAGE |
| Description: | Mouse IL-4 protein (Animal-Free), expressed in HEK293 Cells |
| Further Information: | Interleukin-4 is a pleiotropic cytokine produced primarily by activated T lymphocytes, basophils and mast cells. It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four alpha -helix structure.It plays an important role in the treatment and research of tumor and autoimmune diseases, in addition to its role in mediating inflammatory allergic reaction. Mouse IL-4 is synthesized with a 24 aa signal sequence.Multiple immune response-modulating functions are performed by IL-4 on a variety of cell types and it has an important role in the regulator of isotype switching, induction of IgE production in B lymphocytes and differentiation of precursor T helper cells. IL-4 binds to both membrane-bound and secreted soluble IL-4 receptors. |
| NCBI EntrezGene: | 16189 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Lyophilized Mouse IL-4 protein (Animal-Free)should be stored desiccated below -20 C. Upon reconstitution, the protein should be stored at 4 C between 2-7 days and for future use below -20 C. For long term storage it is recommended to add a carrier protein (0.15% HSA or BSA). Please prevent freeze-thaw cycles. |
| Usage: | Research use only |
