| MW: | 16.7 kDa |
| Purity: | >98% as determined by SDS-PAGE |
| Description: | Human IL-36gamma protein, expressed in E. coli |
| Further Information: | The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36 alpha (IL-1F6), ? (IL-1F8) and gamma (IL-1F9). IL-36gamma is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36gamma signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36gamma also functions as an agonist of NF-?B, and can stimulate the inflammatory response in bronchial epithelial cells. |
| NCBI EntrezGene: | 56300 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Lyophilized Human IL-36gamma proteinshould be stored desiccated below -20 C. Upon reconstitution, the protein should be stored at 4 C between 2-7 days and for future use below -20 C. For long term storage it is recommended to add a carrier protein (0.106% HSA or BSA). Please prevent freeze-thaw cycles. |
| Usage: | Research use only |
