| Applications: | WB, ICC, IF |
| Species Reactivity: | Human, Mouse, Bovine, Chimpanzee |
| Dilutions: | WB (1:2000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user. |
| Immunogen: | GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus |
| Purification: | Protein G Purified |
| Conjugation: | Unconjugated |
| Description: | MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
