MPP+-d3(iodide) [CAS 207556-07-8]
Partner: MedChemexpress LLC
| CAS No: | 207556-07-8 |
| Applications: | Neuroscience-Neuromodulation |
| MW: | 300.15 |
| Formula: | C12H9D3IN |
| SMILES: | [2H]C([2H])([2H])[N+]1=CC=C(C2=CC=CC=C2)C=C1.[I-] |
| Purity: | 99.60 |
| Description: | MPP+-d3 (iodide) is deuterium labeled MPP+ (iodide). MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT)[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
Insight Biotechnology Ltd reserves the right to change pricing without notice
