| Description: | NFYA Protein, a component of the NF-Y transcription factor, recognizes the 5'-CCAAT-3' box motif in gene promoters. NFYA functions as an activator or repressor based on interacting cofactors. It positively regulates the transcription of the core clock component BMAL1. NF-Y, a heterotrimeric transcription factor, requires NF-YB and NF-YC dimerization for NFYA association and DNA binding. NFYA interacts with SP1 and ZHX2, while glycosylation inhibits the SP1 interaction. It also interacts with ZHX1 and ZFX3. NFYA Protein, Human is the recombinant human-derived NFYA protein, expressed by E. coli, with tag free. The total length of NFYA Protein, Human is 318 a.a., with molecular weight of 40 & 60 & 70 kDa, respectively. |
