| Description: | SCF Protein, a ligand for KIT receptor-type protein-tyrosine kinase, regulates diverse cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways, involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinases, STAT family members, and PLCG1, producing diacylglycerol and inositol 1,4,5-trisphosphate. SCF, with likely interleukins, forms homodimers and a heterotetramer with KIT, facilitating dimerization and activation through autophosphorylation. SCF Protein, Human (HEK293, His) is the recombinant human-derived SCF protein, expressed by HEK293, with C-6*His labeled tag. The total length of SCF Protein, Human (HEK293, His) is 189 a.a., with molecular weight (glycosylation form) of 30-50 kDa. |
