| Description: | MXRA8 Protein, a transmembrane modulator, likely interacts with integrin ITGAV:ITGB3, influencing various signaling pathways. It inhibits osteoclastogenesis, promotes cartilage formation, and stimulates primary cilia formation in chondrocytes. In angiogenesis, it suppresses endothelial cell migration, promotes apoptosis, and inhibits VEGF-induced AKT and p38 MAP kinase activation. Additionally, MXRA8 may contribute to arthritogenic alphavirus pathogenesis as a viral receptor. MXRA8 Protein, Human (HEK293, His) is the recombinant human-derived MXRA8 protein, expressed by HEK293, with C-His labeled tag. The total length of MXRA8 Protein, Human (HEK293, His) is 322 a.a., with molecular weight of 40-53 kDa. |
