| Description: | SCF Protein, a ligand for KIT receptor-type protein-tyrosine kinase, regulates diverse cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways, involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinases, STAT family members, and PLCG1, producing diacylglycerol and inositol 1,4,5-trisphosphate. SCF, with likely interleukins, forms homodimers and a heterotetramer with KIT, facilitating dimerization and activation through autophosphorylation. Animal-Free SCF Protein, Human (His) is the recombinant human-derived animal-FreeSCF protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free SCF Protein, Human (His) is 164 a.a., with molecular weight of ~19.4 kDa. |
