(D)-PPA 1 (TFA)
Partner: MedChemexpress LLC
| MW: | 1669.67 |
| Formula: | C72H99F3N20O23 |
| SMILES: | O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC5=CC=CC=C5)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(N)=O)N.OC(C(F)(F)F)=O |
| Purity: | 99.84 |
| Description: | (D)-PPA 1 TFA is a hydrolysisresistant d-peptide antagonist. (D)-PPA 1 TFA serves as a potent PD-1/PD-L1 inhibitor. (D)-PPA 1 TFA binds to PD-1 with the affinity 0f 0.51 ?M with in vitro and in vivo efficacy[1]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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