Data Sheet

MSDS

187-1, N-WASP inhibitor [CAS 380488-27-7]

CAS No:	380488-27-7
Applications:	COVID-19-immunoregulation
MW:	1784.11
Formula:	C₉₆H₁₂₂N₁₈O₁₆
SMILES:	O=C1N2C(C(=O)N[C@H](CC3=CC=CC=C3)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N5[C@@](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CC6=CC=CC=C6)C(=O)N7C(C(=O)N[C@H](CC8=CC=CC=C8)C(=O)N[C@@H](CC9=CC=CC=C9)C(=O)N%10[C@@](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CC%11=CC=CC=C%11)(CCC%10)[H])(CCC7)[H])(CCC5)[H])(CCC2)[H]
Purity:	99.86
Description:	187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 ?M. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein[1][2].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only