PLX-4720 [CAS 918505-84-7]
Partner: MedChemexpress LLC
CAS No: | 918505-84-7 |
Applications: | Cancer-Kinase/protease |
MW: | 413.83 |
Formula: | C17H14ClF2N3O3S |
SMILES: | O=S(NC1=CC=C(C(C(C2=CNC3=NC=C(C=C23)Cl)=O)=C1F)F)(CCC)=O |
Purity: | 99.91 |
Description: | PLX-4720 is a potent and selective inhibitor of�B-RafV600E�with�IC50�of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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