Upadacitinib [CAS 1310726-60-3]
Partner: MedChemexpress LLC
CAS No: | 1310726-60-3 |
Applications: | COVID-19-immunoregulation |
MW: | 380.37 |
Formula: | C17H19F3N6O |
SMILES: | O=C(N1C[C@@H](CC)[C@@H](C2=CN=C3C=NC(NC=C4)=C4N32)C1)NCC(F)(F)F |
Purity: | 99.97 |
Description: | Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research[1][2]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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