Data Sheet

MSDS

MRK-898 [CAS 461450-30-6]

CAS No:	461450-30-6
MW:	400.30
Formula:	C₂₀H₉F₅N₄
SMILES:	N#CC1=CC(F)=CC=C1C2=C(F)C=CC(C3=CN=C4N=C(C(F)(F)F)C=CN43)=C2
Purity:	99.31
Description:	MRK-898 is an orally active GABA(A) receptor modulator. MRK-898 binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively. However, α1-containing GABA(A) receptors are identified as the sedative and α2- and/or α3-containing receptors as the anxiolytic subtype(s)[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only