CC214-2 [CAS 1228012-18-7]
Partner: MedChemexpress LLC
| CAS No: | 1228012-18-7 |
| Applications: | Cancer-Kinase/protease |
| MW: | 383.44 |
| Formula: | C20H25N5O3 |
| SMILES: | O=C1N=C2NC=C(C3=CC=C(C(C)(C)O)N=C3)N=C2N(CC4CCOCC4)C1 |
| Purity: | 98.41 |
| Description: | CC214-2 is an oral active and selective mTOR kinase inhibitor. CC214-2 targets to both of mTORC1 (pS6) and mTORC2 (pAktS473). CC214-2 induces autophagy, which is a potential target for host-directed therapy (HDT) in tuberculosis. CC214-2 exhibits synergistic bactericidal and sterilizing activity agasinst tuberculosis (TB), and shortens the treatment duration. CC214-2 also inhibits Rapamycin (HY-10219)-resistant signaling and the growth of glioblastomas in vitro and in vivo[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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