Data Sheet

MSDS

Onalespib [CAS 912999-49-6] (10mM in DMSO)

CAS No:	912999-49-6
Applications:	Cancer-programmed cell death
MW:	409.52
Formula:	C₂₄H₃₁N₃O₃
SMILES:	OC1=CC(O)=C(C(C)C)C=C1C(N2CC(C=CC(CN3CCN(C)CC3)=C4)=C4C2)=O
Purity:	99.62
Description:	Onalespib (AT13387) is a potent and cross the blood-brain barrier heat-shock-protein-90 (Hsp90) inhibitor. Onalespib inhibits the proliferation, survival and migration. Onalespib decreases the expression of EGFR, p-EGFR, AKT, P-AKT, ERK1/2, P-ERK1/2, S6, P-S6 protein. Onalespib shows antitumor activity. Onalespib has the potential for the research of non-small cell lung cancer (NSCLC)[1][2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only