Data Sheet

MSDS

Camonsertib [CAS 2417489-10-0]

CAS No:	2417489-10-0
Applications:	Cancer-Kinase/protease
MW:	410.47
Formula:	C₂₁H₂₆N₆O₃
SMILES:	O[C@@]1(C[C@H]2O[C@H](CC2)C1)C3=C4C(N(C5=NNC=C5)N=C4)=NC(N6[C@@H](COCC6)C)=C3
Purity:	99.75
Description:	Camonsertib (RP-3500) is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. Camonsertib shows 30-fold selectivity for ATR over mTOR (IC50=120 nM) and >2,000-fold selectivity over ATM, DNA-PK, and PI3K? kinases. Camonsertib has potent antitumor activity[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only