Data Sheet

MSDS

Gamcemetinib [CAS 1887069-10-4]

CAS No:	1887069-10-4
Applications:	COVID-19-immunoregulation
MW:	469.94
Formula:	C₂₂H₂₀ClN₅O₃S
SMILES:	O=C1C2=C(NC[C@H](N1)C)C3=C(S2)C=CC4=NC(OC5=NC(Cl)=NC=C5COCC)=CC=C34
Purity:	98.91
Description:	Gamcemetinib (CC-99677) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). Gamcemetinib is extracted from patent WO2020236636, compound 1[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only