Data Sheet

MSDS

GNF-5837 [CAS 1033769-28-6] (10mM in DMSO)

CAS No:	1033769-28-6
Applications:	Cancer-Kinase/protease
MW:	535.49
Formula:	C₂₈H₂₁F₄N₅O₂
SMILES:	O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=C\C5=CC=CN5)=C2
Purity:	99.45
Description:	GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) [1].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only